Oligodendrocyte Centronuclear myopathy Duchenne muscular dystrophy Fibrosis Glucocorticoid-receptor Antisense oligonucleotide CTG repeats Maximal force Skeletal muscle CONGENITAL MYATHENIC SYNDROME Autophagy Transgenic mouse model Male Myotonic dystrophy mouse models Myotonic Dystrophy Mice Expression Mouse model Motoneuron Long read sequencing Dynamin 2 MBNL ACETYLCHOLINESTERASE CRISPR/Cas9 Gene Therapy Muscular dystrophy Dilated cardiomyopathy Dystrophie myotonique RNA biology Exercise Central nervous system Cell culture model Therapy Diaphragm Muscle CTG repeat contractions AAV Animals Trinucleotide repeat expansion Myostatin Humans KNOCKOUT MICE GSK3␤ Heart Desmin Myotonic dystrophy Myotonic Dystrophy type 1 CRISPRi In vivo RNA splicing Trinucleotide Repeat Expansion Myelin Oligodendrocytes ARN DMPK PacBio Aging DMSXL mice Quantitative microdialysis Antisense oligonucleotides Brain Exercice Dystrophin BIOLOGIE MOLECULAIRE CMS Astrocyte Neuron Cell model Thérapie génique Astrocytes Mouse models Glucocorticoids Myotonic Dystrophy Type 1 Gene therapy Hypoxia Transcriptomics Myotonic dystrophy type 1 Knockout Heart failure Acetylcholinesterase knockout mouse Glial cells Glutamate Gene editing DM1 Endurance training PCR RNA interference Cardiac muscle Acute coronary syndrome Cell penetrating peptide Brain dysfunction Dystrophie Myotonique Intermediate filament CTG repeat instability Cytoskeleton Genotype phenotype correlation Alternative splicing Acetylcholinesterase deficiency GABA Transgenic mouse